Figure 3:Cell cycle analysis of polyploid cells from placenta/embryos at E13 sired by tamoxifen treated male rats. Representative DNAFCM histograms of Propidium iodide stained cells in different phases of cell cycle. (A) Placental cells from control group, (B) Cells from resorbing embryos from control group, (C) Placental cells from treated group, (D) Cells from resorbing embryos from treated group. ‘AP’ indicates Sub-G1 peak comprising of dead and apoptotic cells; ‘G1’ indicates G0/G1 peak; ‘S’ indicates S phase and ‘G2’ indicates G2/M peak. (E) Graphical representation of percentage of cells in different phases of cell cycle in the placenta of embryos at E13 belonging to control normal (CP), control resorbing (CR), tamoxifen treated normal (TP) and tamoxifen treated resorbing groups. Data are presented as Mean ± SEM values (n = 5). ‘*’ significant difference (P ≤ 0.05) when compared to normal embryo from control group.